Stabilized Oil Soluble Vitamin C with Comprehensive Efficacy
- NIKKOL VC-IPVS

HISTORY

NIKKOL GROUP pioneered the commercialization of an oil-soluble version of a vitamin C derivative in 1961. Utilizing its expertise on colloid dermatological science, NIKKOL VC-IP was designed as an ester for high stability during processing and with high percutaneous absorption on skin versus water-soluble derivatives.
After 25 years, we have developed NIKKOL VC-IPVS, a natural grade derived from responsibly-sourced palm ingredients; it is also vegan-friendly and HALAL-certified (MPJA).

Timeline

1961
Developed and launched lipophilic Vitamin C derivative. (World’s 1st)
1986
NIKKOL VC-PMG was launched as novel quasi-drug whitening active.
1997
NIKKOL VC-IP was released.
2009
NIKKOL VC-IPEX obtained QD whitening active status in Japan.
2010
NIKKOL VC-IP obtained functional ingredient for skin lightening in South Korea.
2022
NIKKOL VC-IPVS was launched.

PROVEN EFFICACY

NIKKOL VC-IP NIKKOL VC-IPVS PRODUCT BROCHURE 2021 EDITION

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Papers

· A new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), prevents UV-induced skin pigmentation through its anti-oxidative properties
Yasunobu Ochiai 1, Satoko Kaburagi, Kei Obayashi, Nobuyuki Ujiie, Satoru Hashimoto, Yuri Okano, Hitoshi Masaki, Masamitsu Ichihashi, Hiromu Sakurai
Journal of Dermatological Science, 28 Aug 2006, 44(1):37-44
· Effect of a new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), on senile lentigo via controlling melanocytes-keratinocytes interaction.
Mariko Yokota
Presented at IFSCC conference 2017
· Improvement of Hair Damage by Lipophilic Vitamin C (Ascorbyl Tetraisopalmitate)
Takeshi Misono, Shunsuke Yanaguchi, Satoru Hashimoto
Journal of SCCJ, 2018, 52(3), 205-209
· Evaluation of the anti-wrinkle effect of a lipophilic pro-vitamin C derivative, tetra-isopaimitoyl ascorbic acid
Mariko Yokota, Shoichi Yahagi
J Cosmet Dermatol, 2021;00:1-12

SUSTAINABILITY

NIKKOL VC-IP is primarily manufactured at Nippon Surfactant Industries in Utsunomiya city in Japan. This factory is famous for its eco-friendly, sustainable policies through these local & globally-recognized certifications or activities.

1.
Engages in Eco Action 21 since 2012 - a certifying body authorized by Japan’s Ministry of Environment that promotes companies to improve their own environmental management systems.
2.
Joined the global RSPO supply chain group in 2018. Currently, the factory produces more than 300 products that are RSPO-MB certified.
3.
Awarded “Silver” in the global sustainability ratings index- EcoVadis every year since 2019.
  • Certification# 0008695
  • SILVER 2021 ecovadis

Carbon conscious processes for NIKKOL VC-IPVS

NIKKOL VC-IP VS is manufactured using a dedicated reactor for Vitamin C derivatives. Several processes are in place to continually reduce carbon emissions from its processing. Specifically, these are the systems involved in the manufacturing of this product:

1.
Utilizing gas co-generation system to generate 2 types of energy- electricity & heat to power reactors and boil water.
2.
Optimizing the esterification process- shortened reaction time.
3.
Re-using stored condensed water from other processes to cool down the reaction.
4.
Recovery and recycling of used organic solvents used in the process.

CO2 emission reduction

*Calculated using the US environmental protection agency greenhouse gas calculator

Inquiry

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Areas of Support

Formulation Helper
Surfactant Chemistry Support

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